Antimycobacterial Activity of Isolated Compounds from Lippia Javanica and Hoslundia Opposita
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چکیده
Eight compounds isolated from Lippia javanica and three compounds, from Hoslundia opposita were tested against Mycobacterium tuberculosis at concentrations of 200, 100, 50 and 25μg/ml. Compound “6-Methoxyluteolin 4'-methyl ether” isolated from L. javanica exhibited a minimum inhibitory concentration (MIC) of 200 μg/ml against M. tuberculosis. Of all the compounds tested against a drug-sensitive strain of M. tuberculosis, euscaphic acid was found to show the best activity exhibiting an MIC of 50 μg/ml against this strain. The remaining compounds were found to be inactive at the highest concentrations tested.
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